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back to DBM Case Studies Early Growth in Posterolateral Spine Fusion with the Use of Demineralized Bone Matrix (DBM)
History A 42-year-old woman presented with a history of severe intractable low back pain and lumbar radiculopathy. MRI demonstrated L4-L5 significant degenerative disc disease with disc space collapse, foraminal stenosis and grade I spondylolisthesis. Treatment After failure of conservative treatments, the patient underwent bilateral L4-L5 posterior lumbar interbody fusion and posterolateral fusion, supplemented with L4-L5 posterior instrumentation with pedicle screws. The posterolateral fusion was performed using a total of 30cc of DBM granules (150µm to 800µm) soaked in autologous bone marrow aspirated from the patient’s iliac crest.
Postoperative Results and Outcome The postoperative course was uneventful. Neither generalized nor local adverse reactions were observed postoperatively. Follow-up radiographs were obtained at six months after the surgery. The AP X-rays demonstrated clear evidence of early bilateral posterior lateral fusion (Fig. 1). Further follow-up evaluation is planned.
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Figure 1. 6 Months Postoperative: bilateral fusion mass is clearly visible in the posterior lateral regions on AP views.
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